Innovative Nutritional approach to attenuate the progression of HIV to AIDS among People Living with HIV (PLWH): A study based in Abuja, Nigeria.

  • Abraham Mainaji Amlogu State House Medical Centre, P.M.B 316, Aso Rock, Abuja, Nigeria,
  • Sundus Tewfik School of Human Sciences, Faculty of Life Sciences – London Metropolitan University
  • Charles Wambebe Department of Pharmaceutical Sciences, Tswane University of Technology Pretoria, South Africa
  • Ihab Tewfik School of Life Sciences – University of Westminster, London, 115 New Cavendish Street, W1W 6UW, UK

Abstract

The success of recent nutrition interventions in HIV demonstrate the progress made in HIV care and support. The idea to adapt principles and technologies from the TFR concept to the development of a functional recipe to slow the progression of HIV to AIDS proves to be meaningful and realisable in Amtewa meal nutrition intervention approach.

Although the achieved results take the form of specific technology, it suggests that a prolong consumption of the intervention meal (Amtewa) will be suitable to sustain the gained improvements in the anthropometric and biochemical indices. The research highlighted crucial issues and identified key design parameters that require further attention and research in developing countries like Nigeria.  

Overall, it addresses the synergistic relationship between nutrition and HIV infection, the nutritional requirement and nutritional care and support for PLWHIV in Nigeria. While the nutrition intervention demonstrated a positive effect, the study also suggests that the initial visit of a newly diagnosed HIV-positive patient should include screening for nutritional status, identify risks and offer appropriate nutrition counseling which was not in existence but currently has been imbedded as “Nutritional Framework” within the HIV care and support programme in one of the accredited HIV treatment centres in Nigeria. This Nutritional Framework has provided information to PLWHIV on their HIV medication and food interactions and about nutritional screening tools available in the health setting.

Finally, the research provides evidence which may be used as a basis for policy makers to incorporate Amtewa meal nutrition intervention in HIV care and support programme in other HIV treatment centres in Nigeria with a view of attenuating the progression of HIV to AIDS amongst PLWHIV in Nigeria. 

Downloads

Download data is not yet available.

References

AIDSinfo, (2014). The HIV life cycle.(Online). Available: http://aidsinfo.nih.gov/education-materials/fact-sheets/19/73/the-hiv-life-cycle. (Accessed 18/04/14).
AIDS, (2013). Stages of HIV infection. (Online). AIDS.Gov. Available: http://aids.gov/hiv-aids-basics/just-diagnosed-with-hiv-aids/hiv-in-your-body/stages-of-hiv/. (Accessed 5/1013).
AIDS, (2009). HIV life cycle.(Online). AIDS. Gov. Available: http://aids.gov/hiv-aids-basics/just-diagnosed-with-hiv-aids/hiv-in-your-body/hiv-lifecycle/index.html. (Accessed 10/10/13).
Amlogu, M A., Tewfik, S., Wambebe, C., Godden, K. and Tewfik, I. (2011). Conceptual framework of public health-nutrition intervention programme toattenuate the progression of HIV to AIDS among People Living with HIV(PLWH) in Abuja, Nigeria. In Sharing Knowledge Making a Difference: The Roleof International Scientific Cooperation, World Sustainable DevelopmentOutlook 2011.ISBN 978-1-907106-12-5, 11-20.
Amlogu, A M., Godden, K., Tewfik, S., Wambebe, C. & Tewfik, I. (2012). TailoredFood Recipe – TFR: Employing the European perspective on functional foodscience (FUFOSE) to promote effective dietary intervention in Africa. International Journal of Food, Nutrition & Public Health, 5 (1/2/3), 1-10.
Amlogu, A M., Godden, K., Tewfik, S., Wambebe, C. & Tewfik, I. (2013). Public Health Nutrition Intervention Programme to Attenuate the Progression of HIVto AIDS among People Living with HIV (PLWH) in Abuja, Nigeria: A Conceptual Framework International Journal of Food, Nutrition & Public Health, 6 (1): 83-98.
Amlogu, A M., Tewfik, S., Wambebe, C. & Tewfik, I. (2014). Tailored Functional Recipe (TFR) approach to delay the progression of HIV to AIDS among People Living with HIV (PLWH) in Abuja, Nigeria. Scientific Research Journal of Pharmacology & Pharmacy, 5: 925 – 936.
Amuna, P., Zotor, F. and Tewfik, I. (2004). Human and Economic Development in Africa: A Public Health Dimension employing the food multimix (FMM) concept. World Review of Science, Technology and Sustainable Development, 1 (2), 45-55.
Anabwani, G. and Nazario, P. (2005). Nutrition and HIV/AIDS in sub-Saharan Africa; An overview. The International Journal of applied and basic nutritional sciences, 21, 96-99.
Barry, E., Johanna, R., Maria, M., Alex, G., Peter, J., Kevin, J., Jeffrey, M., Marianna, K., Gail, S., Jay, S. & Neil, S. (2007). Suppression of Human Immunodeficiency Virus Type 1 Viral Load with Selenium Supplementation; A randomized controlled trial. Achieves of internal medicine, 167 (2), 148-154.
Baum, M K., Shor-Posner, G., Lu, Y., Rosner, B., Sauberlich, H E., Fletcher, M A., Szapocznik, J., Eisdorfer, C., Buring, J E., Hennekens, C H., (1995). Micronutrients and HIV – 1 disease progression. AIDS, 9(9):1051- 6.
Beach, R S., Mantero-Atienza, E., Shor-Posner, G., Javier, JJ., Szapocznik, J., Morgan, R., Sauberlich, H E., Cornwell, PE., Eisdorfer, C., Baum, M K., (1992). Specific nutrient abnormalities in asymptomatic HIV 1 infection. AIDS, 6(7):701- 8.
Bendich, A. and Langseth, L. (1995). The health effect of Vitamin C Supplementation: A review. J. Am Coll Nutr, 14: 124-136.
Bijlsma, M. (2000). Nutritional care and support for people with HIV, Review of Literature, initiatives and educational materials in Sub-Saharan Africa and recommendations for developing national Programmes Report to FAO 2000.
Bishop, C W., Bowen, P E., Ritchey, S J., (1981). Norms for nutritional assessment of American adults by upper arm anthropometry. Am J Clin Nutr., 34: 2530 – 2540.
Boon, N A., Walker, B R. (2006).Davidson’s principle and practice of medicines.20th ed. USA; Elsevier. USA.
Centres for Disease Control and Prevention, (2014). HIV/AIDS. (Online). CDC.Gov. Available: http://www.cdc.gov/hiv/basics/whatishiv.html. (Accessed 5/4/14).
Central Intelligence Agency (CIA), (2012). The World FactBook: HIV/AIDS Adult prevalence rate. (online). Available: https://www.cia.gov/library/publications/the-world-factbook/rankorder/2155rank.html. (Accessed 20/2/14).
Cimoch, P. (1997). Nutritional health prevention and treatment of HIV – associated malnutrition.A case manager’s guide. International Association of physicians in AIDS Care.
Diplock, A T., Charleux, J L., Crozier-Willi, G., Kok, F J., Rice-Evans, C., Roberfroid, M., Stahl, W., Viña-Ribes, J., (1998). Functional Food Science and defence against oxidative species. British Journal of Nutrition, 80(Suppl. 1): S77 – S112.
Drain, P K., Kupka, R., Mugusi, F. and Fawzi, W W. (2007). Micronutrients in HIV-positive persons receiving highly active antiretroviral therapy. Am J Clin Nutr,85 (2) 333-45.
Duggal, S., Chugh, T.D. and Duggal, A.K. (2012). Review article on HIV and Malnutrition: Effect on Immune System. Journal of Immunology Research, (online). Available: http://www.hindawi.com/journals/jir/2012/784740/ref/. Accessed 2/4/14).
EUFIC, (2006). Functional Food. European Food Information Council. (online). Available: http://www.eufic.org/index/en (Accessed 10/12/11)
FANTA, (2004). HIV/AIDS: A Guide for Nutritional Care and Support. 2nd Edition.Food and Nutrition Technical Assistance Project.Academy for Educational Development, Washington DC, 2004.(online). Availablet: http://www.fantaproject.org/publications/HIVguide.shtml. (Accessed 6/3/12).
FANTA/USAID, (2007).Recommendation for Nutrient requirement for People Living with HIV/AID. February, 2007.
FAO, (2014). Corporate Document Repository: Nutrition in the developing world. (online). Available: http://www.fao.org/docrep/w0073e/w0073e03.htm#P690_92639. (Accessed 20/04/14).
FAO, (2010). FAO Hunger Map. (online). Available: http://www.fao.org/fileadmin/templates/es/Hunger_Portal/Hunger_Map_2010b. (Accessed 15/12/14).
FAO/WHO, (2002). Living well with HIV/AIDS – A manual on nutritional care and support for people living with HIV/AIDS.Rome, Food and Agriculture Organization. Available at:http://www.fao.org/DOCREP/005/Y4168E/Y4168E00.htm. (Accessed 10/12/10).
Fawzi, W. (2003). Micronutrients and human immunodeficiency virus type 1 disease progression among adults and children. Clinical Infectious Diseases, 37(S2):112-116.
Federal Ministry of Health, (2005). National HIV seroprevalence sentinel survey. National AIDS/STDs control programme. FMOH, Abuja, Nigeria.
Federal Ministry of Health (FMOH), (2007). National Action Plan for Delivery of HIV/AIDS Palliative Care Services in Nigeria 2008-2009.FMOH, Abuja.
Federal Ministry of Health, (2007). National Guidelines for HIV and AIDS Treatment and Care in Adolescents and Adults. FMOH, Abuja, Nigeria.
Federal Ministry of Health, (2010). National Guidelines for Prevention of Mother-To-Child Transmission of HIV (PMTCT). FMOH, Abuja, Nigeria.
Federal Ministry of Health, (2010). National Guidelines for Paediatric HIV and AIDS Treatment and Care. FMOH, Abuja, Nigeria.
Federal Ministry of Health, (2011). Guidelines on Nutritional Care and Support for People Living with HIV in Nigeria. FMOH, Abuja, Nigeria.
International Institute of Tropical Agriculture (IITA), (2004). Nigeria Food Consumption and Nutrition Survey 2001 – 2003. Ibadan, Nigeria.
Ivers, L C., Cullen, K A., Freedberg, K A., Block, S., Coates, J., and Webb, P., (2009). HIV/AIDS, undernutrition and food insecurity. Clin Infec Dis, 49:1096 - 1102.
Kokler, D P. (1992). Nutritional effects and support in patient with acquired immunodeficiency syndrome. J. Nutr 122: 723-729.
Kotler, D P., Rosenbaum, K., Wang, J., Pierson, R N., (1999). Studies of body composition and fat distribution in HIV-infected and control subjects.Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology: Official Publication of the International Retrovirology Association, 20(3):228 - 237.
Kupka, R., Msamanga, G I., Spiegelman, D., Morris, S., Mugusi, F., Hunter, D J. and Fawzi, W W. (2004). Selenium status is associated with accelerated HIV disease progression among HIV-1-infected pregnant women in Tanzania. Journal of Nutrition, 2004, 134(10):2556-2560.
Kumar, P., and Clark, M. (2005). Clinical Medicines. 6th ed. UK, USA; Elsevier Saunders. USA.
Mahlungulu, S S N., Grobler, L., Visser, M M E. And Volmink, J. (2009). Nutritional interventions for reducing morbidity and mortality in people with HIV (Review). Published by Wiley & Sons.
Melchior, J.D., Salmon, D., Rigaud, D., Leport, C., Bouvet, E., Detruchis, P., Vilde, L.J., Vachon, F., Coulaud, J.P., Apfebaum, M. (1991). Resting energy expenditure is increased in stable, malnourished HIV-infected patients. Am J ClinNutr 1991; 53: 437-41.
Monica, G M., (2013). Miracle Tree. (online). Available: http://www.amazon.com/Miracle-Tree-Monica-Marcu-PHARM/dp/1495946096#reader_1495946096. (Accessed 5/01/14).
National Agency for the Control of AIDS (NACA), (2012). Federal Republic of Nigeria: Global AIDS Response Country Progress Report, Abuja, Nigeria.
Oguntibeju, O O., Van den Heever, W M J and Van Schalkwyk, F E. (2008). Potential effects of nutrient supplement on the anthropometric profiles of HIV-positive patients: Complimentary medicine could have a role in the management of HIV/AIDS. African Journal of Biomedical Research.11: 13 – 22.
Palar, K., Wagner, G., Ghosh-Dastidar, B. and Mugyenyi, P. (2012). Role of antiretroviral therapy in improving food security among patients initiating HIV treatment care. AIDS, 28;26(18):2375-81.
Periquet, B A., Jammes, N M., Lambert, W E., Tricoire, J., Moussa, M M., Garcia, J., Ghisolfi, J., and Thouvenot, J., (1995). Micronutrient levels in HIV-1-infected children. AIDS, 887– 893.
Pribram, V. (2011). Nutrition and HIV. First edition. Wiley-Blakwell, U.K
Piwoz, E G.and Preble, E A. (2000). HIV/AIDS and Nutrition: A Review of the Literature and Recommendations for Nutritional Care and Support in Africa, Academy for Educational Development, Washington, DC, USA,
Piwoz, E. (2004). Nutrition and HIV/AIDS; Evidence, Gaps and Priority actions.The Support for Analysis and Research in Africa project. Washington DC: Academy for Education Development, 49, 190 – 195.
Pope and Haase, (2003). Virology and Immunology of HIV. Nat Med 9(7): 847-852. Available: http://www.itg.be/internet/e-learning/written_lecture_eng/2_virus_entry_in_the_body_cont2.html. (Accessed 2/4/14).
RCQHC and FANTA, (2003). Nutrition and HIV/AIDS: A training manual nutritional management of HIV/AIDS related symptoms. Available: http://wwwfantaproject.org/focus/preservice.shtml. (Accessed December, 2010).
Roberfroid, M B., (2000). Concepts and Strategy of Functional Food Science: the European perspective. Am J Clin Nutrition. 71 (Suppl): 1660S-4S.
Tang, A M. and Smit, E. (1998). Selected vitamins in HIV infection: a review. AIDS patient care STDS. 12(4): 263 – 73.
Tang, A M., Graham, N M., Chandra, R K. and Saah, A J. (1997). Low serum vitamin B-12 concentration are associated with faster human immunodeficiency virus type 1 (HIV – 1) disease progression. J Nutr. 127 (2): 345 – 51.
Tang, A M., Forrester, J., Spiegelman, D., Knox, T., Tchetgen, E., Gorbach, S L. (2002).Weight loss and survival in HIV-positive patients in the era of Highly Active Antiretroviral therapy.Journal of Acquired Immune Deficiency Syndrome.31, (2), 230-236.
Tewfik, I., Bener, A. and Tewfik, S. (2010). Is Africa facing a nutritional transition under the double burden o f disease? World Association for Sustainable Development 1, 160-171.
The Naked Scientist, (2007). The Science of HIV and AIDS in the U.K. (online). Available: http://www.thenakedscientists.com/HTML/articles/article/25yearsofhivaidsintheuk/. (Accessed 5/3/14).
Ukibe, N R., Onynekwe, C C., Ahaneku, J E., Ukibe, S N., Meludu, S C., Emelumadu, O F., Ifeadike, C O., Ilika, A L., Ifeanyichukwu, MO., Igwegbe, AO., (2013). Evaluation of nutritional status of HIV infected females during menstrual cycle in Nnewi, Anambra State, Nigeria. Scientific Journal of Medical Sciences, 2 (9).
UNAIDS, (2008). Report on the global Aids epidemic. (online). Available: http://www.aids2031.org/pdfs/unaids_08executivesummary_en(1).pdf. (Accessed 15/11/14).
UNAIDS and WHO, (2009). AIDS epidemic update. UNAIDS/09.36E/JC1700E (English original, November 2009) UNAIDS, Geneva, Switzerland.
UNAIDS, (2010). Global Report on the Global AIDS Epidemic 2010. (online). Available: http://www.unaids.org/globalreport/documents/20101123_GlobalReport_full_en.pdf. (Accessed 10/01/14).
UNAIDS, (2011). Report on the global Aids epidemic.(online). Available: http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/2011/20111130_ua_report_en.pdf. (Accessed 15/04/12).
USAID, (2004).Nutrition and HIV/AIDS; Evidence, Gaps and Priority Actions (online). Available at: http://www.fantaproject.org/downloads/.../SARA_Nutrition&HIV. Accessed 7/10/09).
Vajpayee, M., Kaushik, S., Sreenivas, V., Wig, N., Seth, P. (2005). CDC staging based on absolute CD4 count and CD4 percentage in an HIV-1-infected population: treatment implications. Clin. Exp. Immunol. 141(3): 485-490.
Van Staden, A M., Barnard, H C. and Nel, M. (1998). Nutritional status of HIV – 1 seropositive patients in the Free State Province of South Africa – Laboratory Parameters. Centr Afr J Med 44 (10) : 240 – 50.
Vilaseca, M A., Artuch, R., Sierra, C., Pineda, J., Lopez-Vilches, M A., Munoz-Almagro, C., Fortuny, C., (2003). Low serum carnitine in HIV – infected children in antiretroviral treatment. European Journal of clinical Nutrition, (57):1317 - 1322
Wang, E A., McGinnis, K A., Fiellin, D A., Goulet, J L., Bryant, K., Gibert, C L., Leaf, D A., Mattocks, K., Sullivan, L E., Vogenthaler, N., Justice, AC., (2011). Food insecurity is associated with poor virologic response among HIV-infected patients receiving antiretroviral medications. J Gen Intern Med, 26(9) :1012 - 8.
WHO, (2003). Nutrient requirements for people living with HIV/AIDS: Report of a technical consultation. WHO, Geneva, Switzerland.
WHO, (2005).Executive summary of a scientific review.Consultation on nutrition and HIV/AIDS in Africa.Evidence, lessons and recommendations for action. Durban, South Africa, 10-13 April 2005. Geneva, World Health Organization.
World Health Organisation, (2006). WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adult and children. WHO Press. World Health Organisation, Geneva, Switzerland.
WHO, (2010).New WHO HIV treatment and prevention guidelines. (online). Available: www.thelancet.com . (Accessed 20/07/10).
WHO, UNAIDS and Unicef, (2011). Global HIV/AIDS Response: Epidemic update and health sector progress towards universal access. (online). Available: http://www.unaids.org/en/media/unaids/contentassets/documents/unaidspublication/2011/20111130_ua_report_en.pdf. (Accessed 10/04/14).
World Health Organisation, (2013).Nutrition activities in care, support and treatment of HIV/AIDS. Situation Analysis for SEAR countries based on preliminary desk review and inputs from member countries. (Online).World Health Organisation. (online). Available: http://www.who.int/nutrition/topics/Situation_Analysis_for_SEAR_Countries.pdf (Accessed 20/12/13)..
World Health Organisation, (2013). HIV/AIDS. (online).World Health Organisation. Available: http://www.who.int/topics/hiv_aids/en/ (Accessed 20/12/13).
World Health Organisation, (2013). HIV/AIDS. (online).World Health Organisation. Media Centre. Available: http://www.who.int/mediacentre/factsheets/fs360/en/ (Accessed 10/11/13).
Zotor, F., Amuna, P., Oldewage-Theron, W H., Adewuya, T., Prinsloo, G., Chinyanga, Y., Tewfik, I. and Amuna, N. (2006). Industrial and dietetic applications for the food multimix (FMM) concept in meeting nutritional needs of vulnerable groups in South Africa. Academic journal of Vaal University of Technology, 3:54-67.
Published
2019-01-30
How to Cite
Amlogu, A. M., Tewfik, S., Wambebe, C., & Tewfik, I. (2019). Innovative Nutritional approach to attenuate the progression of HIV to AIDS among People Living with HIV (PLWH): A study based in Abuja, Nigeria. Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425), 5(1), 01-28. Retrieved from https://jiaats.com/ojs31/index.php/mhs/article/view/950